Research Peptides Melanotan II

Tanning and Growth Factor Peptides

Peptide Calculator Melanotan Instruction

May 25th, 2011 by peptideguide

http://peptidecalculator.com/melanotan

Melanotan Information

Melanotan II is a cosmetic sunless tanning product that stimulates melanin production. Melanin is the main determinant of skin color in humans, a brown pigment which causes skin to become dark instead of red/burnt when exposed to UV rays. Melanotan II users develop a gradual, natural looking tan with minimal exposure to the sun. It is particularly useful for fair-skinned individuals who cannot tan naturally in the sun.

Melanotan II peptide is not a treatment or cure for any disease, nor should it be used with the aim of preventing skin cancer. While melanin is known to have excellent photo protective properties in the skin, no clinical studies have ever indicated the efficiency of Melanotan II specifically in reducing UV damage. The future will bring improved targeted peptides with increased bioavailability.

Melanotan I (MT-1) vs Melanotan II (MT-2)

It is estimated that more than 95% of Melanotan users are familiar with the injectable Melanotan II. Melanotan I is usually only preferred by a small amount of long-term users who feel that Melanotan II makes them too dark, nauseated, and/or those who find the aphrodisiac side effect of Melanotan II to be a nuisance. These problems can be avoided by taking Melanotan II in lower dosages, administering before bed and using sunscreen and clothing to control tanning.

Melanotan I has a larger body of clinical evidence supporting its safety. New interested sunless tanners often feel that MT-1 would be the better and safer option for usage. Unfortunately Melanotan II works significantly better for tanning. Most users who choose Melanotan I are disappointed with the lack of results as compared to Melanotan II. Melanotan I is suited to improve the pigment of the vs skin darkening.

Melanotan II Storage

In powder (lyophilized) form vials should be stored at refrigerator temperature (2-8 degrees Celsius) where they will remain stable for up to 12 months. Reconstituted (mixed) vials should also be stored in the refrigerator, but use within 8 weeks or they may begin to degrade. They will still be safe to use after this time, but they may not be as effective as new vials.

When to take Melanotan II

The frequency of Melanotan II injections will depend largely on your skin type to begin with, therefore you should identify with which Fitzpatrick skin type you are

Type 1: Pale skin, many freckles, blue/green eyes, red hair, never tans, always burns
Type 2: Fair skin, few freckles, blue/hazel eyes, blonde/sandy hair, tans poorly, usually burns
Type 3: Darker white skin, brown hair/eyes, usually tans, rarely burns
Type 4: Light brown skin, darker brown hair/eyes, tans easily, burns minimally

Sunless Tanning

Loading: Take your Melanotan II dose 1 time per day and continue with daily injections until you are happy with the color of your tan. Maintenance: To maintain your desired tan, inject your Melanotan II dose just 2-3 times per week Cessation: You can continue the maintenance dosing indefinitely; however, if you choose to stop your Melanotan II injections, your tan will fade back to its pre-Melanotan II shade in 1-2 months.

Assuming the right amount of UV exposure (sun or sun bed) is combined with your Melanotan II usage, then the amount of time it takes to achieve your desired tan (i.e. the loading phase) will usually take 4-8 weeks for skin types 1 and 2 and as little as 2-3 weeks for skin types 3 and 4.

Melanotan II and UV Exposure

The tanning activity of Melanotan II without the need for UV exposure has been proven by clinical trial; however, the majority of users report that results are achieved much quicker, and that the tan is a more natural color, when Melanotan II is combined with a small amount of UV exposure.

Tanning should start after the third injection and occur 2-3 times per week if you wish to see tanning results quickly; otherwise one tanning session per week is sufficient to gradually build your tan

Where do I buy Melanotan II Online?

Buy Melanotan II and Melanotan I peptides from Tan Research. Best selling Melanotan tanning peptides shipped from United States.

Tan Research peptides are synthetic analogs of naturally occurring alpha melanocyte stimulating hormone (a-MSH). Melanotropin MT-II stimulates sunless tanning cells which produce melanin. Melanotans have been proven safe and effective.

Melanotan Instruction

If not seeing results you need to increase the frequency of your outdoor or indoor UV exposure (especially if you are skin types 1 or 2).

Tanning sessions should be short, 5-10 minutes in a sun bed or 30-40 minutes in the sun on a warm day is sufficient each time. DO NOT overexpose yourself to UV rays. Protect the face and work to balance your tan.

When starting out always use 30+ sunscreen on sensitive areas such as the face and neck. Because these areas are frequently exposed to UV rays they are more responsive to the melanin producing effects of Melanotan II and therefore will become darker quicker than the rest of the body. Covering these areas initially will allow other parts of the body to tan first, ensuring you achieve a well balanced tan.

Melanotan II and UV exposure complement each other, so if you spend a lot of time tanning you will need less frequent injections of Melanotan II to obtain and maintain your tan. If you don’t spend much time in the sun or sun beds then you will need frequent dosages of Melanotan II to develop and keep your tan

Melanotan II Acetate

Peptide structure: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular formula: C50H69N15O9

Melanotan II Tanning Tips

March 24th, 2011 by peptideguide

Dose escalation. With Melanotan 2, a good starting point is .25 mg. The goal is to find the smallest effective dose possible while limiting side-effects. Everyone is different, not all Melanotan II suppliers are created equal.

Anti-histamines. Anti-histamine use can help reduce post injection nausea from MT-2. The anti-histamine reduces the probability of the body reacting that way to the introduction of the foreign compound. Claritin (Loratadine), Zyrtec (Cetirizine), Benadryl (Diphenhydramine) are appropriate.

Cover your eyes and face. Fair skinned MT-2 users particularly. As limited UV exposure is essential for a natural looking tan, experiment with your body first. Try and avoid exposing your face while on a Melanotan course. Many out there overexpose themselves leaving their faces looking extra dark. Purple lips, wrinkles and freckles are just some of the lovely characteristics misuse can bring. Your face is sensitive, protect it. Achieving a balanced tan is what most of us are after.  Phototherapy is often overlooked and not given enough respect.

Ignore dosing charts. Rely on a common sense approach of dose escalation and experimentation. Charts which float around the net often have not kept up with the collective and advocate dangerously high dosages.

Read current guides. Find the best information from many sources. Misinformation, trends, fades, and propaganda run rampant in the marketplace. Successful how to guides often share many similar principles which are extremely helpful to pay attention to.

Rely on referrals. A seller who has stood the test of time and has referrals is likely looking out for you. A seller or area touting concerns about fillers, standards or origins often are misguided.  Buy Melanotan II

Log & support user logs. Creating or simply participating in user logs offers insight into the thought process of the MT-2 user. The market relies on the collective knowledge. Rare there are detailed instructions applicable to you and your specific objectives. Ask questions. You will be surprised how many tricks of the trade rise to the surface.

Weight-loss. Clinical data is on the rise. For now, many users believe MT-2 has fat loss/appetite suppression possibilities. Maximize fat loss when you use MT-2 on days or during time periods when you are fasting or in a caloric deficit.

Travel sized Peptides. Although reconstituted MT-2 lasts for months when refrigerated, peptides are perishable items and require a certain level of care. 10mg MT-2 has been the industry standard size. With the dosage charts on the decrease, dose escalation on the increase, 5mg MT-2 offers further efficacy. Rather take a 10mg or 5mg MT-2 on a 4 day vacation? What about a 2mg PT-141 for the weekend? These are some options to take note of. From experience I can tell you there is not much exciting about bringing a 10mg vial on a trip only to pitch 5-8mg of the product in the trash before the flight home.

Growth Hormone Releasing Peptide (GHRP-6)

December 13th, 2010 by peptideguide

http://peptide-guide.com/

GHRP-6 (Growth Hormone Releasing Peptide) Dose:

Light:  50mcg
Common:  100mcg
Large:  150mcg

Growth Hormone Releasing Peptide (GHRP-6) is a peptide in the growth factor family.  It has strong effect on the release of Human Growth Hormone (HGH) in a specific and dose-related manner.  GHRP can be effectively used in the treatment of growth hormone (GH) deficiency.  Growth hormone releasing hexapeptide works by signaling the pituitary gland to begin growth hormone secretion.

Increased GH and IGF-1 levels are highly desirable for those looking to improve physique.  Human growth hormone has been known to enhance immune response and stimulate the immune system, particularly older subjects.  Dosed at night for anti-aging purposes and multiple times throughout the day for anabolism.  GHRP is often used in conjunction with GHRH CJC-1295 (GRF 1-29) to amplify growth hormone pulse.  Avoid fats and carbohydrate a half hour on each side of dosing GHRP-6.

Bodybuilders and athletes utilize GHRP in an effort to build more muscle and burn fat.  Some GHRP-6 users include it in their post cycle therapy (PCT).   Cycling GHRP-6 in the off weeks from IGF/GH cycles is also becoming prevalent.  Researchers wish to kick-start their body into producing their own natural GH & IGF, while gaining as if they remained on the GH/IGF peptides.

GHRP-6’s main use is to promote food intake by stimulating hunger and aid in energy metabolism.  The major side effect being a significant increase in appetite due to a stimulating the release of Ghrelin (about 20 minutes post injection), a hormone released naturally in the lining of the stomach and increases hunger and gastric emptying.  This is why GHRP-6 can be used in the treatment of cachexia (wasting), eating disorders and obesity.

Benefits of increased HGH levels through GHRP-6 stimulation include:  an increase in strength, muscle mass and body fat loss, rejuvenation and strengthening of joints, connective tissue and bone mass.  Enhanced HGH secretion also leads to the liver secreting more IGF-1, which is thought to be the primary anabolic mechanism of action for Growth Hormone.

GHRP-6 Peptide: GHRP-6 peptide is typically offered in 5mg vials

GHRP-6

Mixing: Bacteriostatic water is used for reconstitution.  When diluted, peptide lasts a very long time when left alone in the refrigerator (months)

Example-  2.5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately each 2-3 marks on a U100 insulin syringe.
Example-  5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately every 5 marks on a U100 insulin syringe.

Dosing: The saturation dose of GHRP-6 has been determined to be around 100mcg.  More is not better in regards to this secretalogue

5mg GHRP  = 5,000mcg

5,000mcg/100mcg =  50 100mcg GHRP doses per 5mg

GHRP-6 may be the most cost effective secretalogue available today

Melanotan II Guide

February 13th, 2010 by peptideguide

Melanotan 2 Dosing:

Light:  .5mg
Common:  1mg
Large:  1.5mg

Melanotan 2 (MT-II) is an analog of alpha-melanocyte stimulating hormone (a-MSH).  Melanotan 2 comes in the form of a freeze dried (lyophilized) peptide in a sterile multi-use vial.

Research Peptide Melanotan 2 10mg Freeze dried vial

Melanotan 2 acts on melanocytes to stimulate melanin production.  Melanin is the body’s natural pigment responsible for your tan.

Melanocyte and Melanin

Melanocortins are a family of peptides beginning with the sequence: His-Phe-Arg-Trp.  Melanotan peptides bind to and activate melanocortin receptors (MCRs) which influence pigmentation, inflammation, energy homeostasis, appetite and sexual function.  MT-2 MCRs:  MC1R, MC3R, MC4R & MC5R.

Melanotan 2 is a smaller and more potent than M-I (which targets MC1R).  Melanotan 2 has a protective ring-like amino acid structure as compared to a linear peptide such as Melanotan One or Afamelanotide.

MT-2:  Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

What does this mean? The fair skinned CAN achieve a natural tan with synthetic MSH, Melanotan 2.  For people with sun allergies these discoveries are life changing.  The best defense against skin cancer is a natural tan developed over time.  MT-2 was designed to reduce skin cancer rates and be effective as a sunless tanner.

Who uses Melanotan 2? Athletes and fitness enthusiasts choose MT-2 as a lifestyle product to increase tanning efficacy, the aphrodisiac and appetite suppression.  MT-2 was dubbed the Barbie drug and has been highlighted in wired magazine.  Synthetic melanocortin use helps to attain a tan with the least amount of exposure to harmful ultraviolet radiation (UVR).

melanotan 2 before and after photo

Lower skin types on the Fitzpatrick scale are the best candidates for Melanotan 2.

Fitzpatrick skin type scale

Melanotan treatment stimulates melanin effectively, in particular those with low skin types.

Melanotan Effects Melanin DensityMelanotan trial effects
Note: Melanotan is approximately 1,000 times more potent than natural a-MSH and MT-2 has a greater efficacy than M-I.

Disclaimer: Please pursue information regarding the usage of these products from your own research, academic journals, or the research of your in-house scientific team. Products are sold for research purposes are not for human consumption. Remember when you contact these types of stores/sponsors not to relate the questions or topics to human consumption or they tend not to answer.  Always inquire in a research type question.

Melanotan 2 peptide 5mg and 10mg vial sizesMelanotan 2 Peptide: Melanotan 2 peptides come in 5mg and 10mg sizes.  Photograph at left shows a 5mg and 10mg MT-2 peptide as an example.  Peptides within photograph were synthesized by the same laboratory, contain no filler and therefore volume reflects content.  All peptides and freeze drying processes are not created equal.  Current MT-2 industry standard is the 10mg, 2ml vial size.  Trending towards lower doses, freshness, safety, travel and other factors are increasing demand for smaller quantities.  The 5mg MT-2 in the 2ml vial (photographed at left, on the left) size is available exclusively through Tan Research.

Reconstituted with bacteriostatic water (BW), MT-2 peptide remains potent and preserved.  Reconstituting (mixing) your Melanotan 2 peptide is a necessity and will require proper due diligence for results.  Nasal sprays, pre-mixed Melanotan 2, pills, oral and loose powder are not often legitimate.  There are successful reports of nasal spray experiences, however, they are few and far between as the molecule is larger than the membrane will allow.  Enzymes will render the peptide inactive if ingested.

Shipping and Handling: Melanotan peptides are durable and stable.  Highlighted in study, the reconstituted MT-2 was shown to be stable at 37 degrees Celsius (98 degrees Fahrenheit) for at least 28 days.  Shipping MT-2, even in summer months, is not a problem.  Do not pay for cold shipping as it is not a premium.  When receiving MT-2 it is recommended to store in the refrigerator.

Mixing: Add BW to the vial when you are ready to begin MT-2 research.  Remove plastic flip top from vial to expose rubber stopper.  Needle will pierce the stopper making way inside the vial to turn the white powder into a clear liquid.

Calculator: Add 100 units (1ml) of water to the vial. 1ml/100 units will minimize the volume that you have to inject and will simplify the arithmetic in your MT-2 experiment.
http://peptidecalculator.com/

1ml syringe (U100), 1ml BW to reconstitute
Calculations for a desired 0.5mg/500mcg dose:
Step 1= 1ml
Step 2= 10mg MT-II
Step 3= 1ml bact water
Step 4= 500mcg dose
2-3 ticks on your insulin pin (approximately 1/20th of a U100 syringe)

peptide calculator screen shot
Some prefer to add more dilutent which works fine, take note of the volume increase.

Needles: 29-31 gauge X 1/2″, 1 CC (100 unit).  That is a typical insulin needle used to mix as well as inject.  Use needles one time only.  Once your technique perfected, injections are almost painless.

Starting dose: Your first injection should be a very small dose, for example .25mg (250mcg).  See how you react.  Goal should be to feel nothing.  Dose after dinner, before bed.  Any dosing chart stating that you should take a high dose (according to your weight) is outdated and potentially dangerous.

Loading dose: Load with 0.5-1mg once a day.  People who have used doses in this range generally report getting excellent results.  Don’t worry if you miss occasional days.  It will not make much difference, focus on the cumulative effects.

Maintenance dose: Maintenance is taking doses less frequently than daily to avoid becoming darker than you want.  Yes, that will happen.  With enough UVR, you will get much darker than you have even been before.  A maintenance dose can help prolong super-physiological photo-protection MT-2 delivers.

UV Radiation: Melanotan is a poor sunless tanner.  UV (from sun or a tanning bed) light is necessary to develop a tan.  Without it, almost nothing happens.  In other words, NO UV = NO TAN.  Well, user will pigment depending on skin type….  If you have loaded for a full month and then start UV exposure, you (and your friends) will be astounded by how fast you tan and how dark you get.  Moreover, it is advisable to keep areas of your skin that ordinarily get exposure covered up with a towel and/or zinc oxide (nose/lips/face) and let less exposed areas develop pigmentation first. Areas of skin that are typically sun-exposed in your day to day life will respond more readily to the effects of the melanotan peptides.

Fat Loss: The melanocortin (MC) system is a signaling pathway for leptin and insulin.  The MC system is important for control of food intake and body weight.  MT-2 treatment results in adipocyte lipolysis.  MT-2 increases fatty acid oxidation(FAO) in which the MC5R plays a significant role.  MT-2 improves insulin sensitivity through stimulating FAO in skeletal muscle tissue.  Reduced food intake from the anorectic response of MT-2 is primarily responsible for weight loss.

Watch yourself: Your tan can sneak up on you.  A tan generally sets in 3 days after UV rays.  Dose and expose yourself gradually to UVR when tanning.  Love your skin.

Avoid burning:
You are protected from burning mostly by your tan, not the MT-2 peptide.  Therefore, don’t overdo the rays at first.  Start with only as much UV that you could tolerate without burring before you began Melanotan.  It should not take many weeks before you can tolerate hours of strong sun without burning.  Truly incredible for those who have never experienced freedom to enjoy the sun.

Continue your regular dosing protocol until you have reached your desired tan and do not want to become darker.  Cut injection frequency to once every 2, 3, 4, or even 7 days.  Experiment to find the frequency that gives the tan you want.

Storage: Store freeze dried and reconstituted peptides in the refrigerator.

Do you have to inject MT-II?
Yes.  The best, most efficient method of administering Melanotan peptides are subcutaneous (subq) injections.  Nasal sprays are inconsistent and inefficient.  No detectable levels were observed following oral dosing – pills do not work.
subcutaneous injection photo

Note:  There are many things you will need to consider before experimenting with this peptide.  MT-II is not an approved drug, anywhere.  MT-II is legal to buy, possess, etc.  Variables such as skin type and individual goals need assessment, create a user log.  Seasoned users are generally more than happy to critique and offer tricks of the trade.

When you start supplementing a-MSH to tan keep in mind that tanning is literally a side effect. Melanocyte stimulating hormone is not going to color your skin, it is going to make your own skin create its own tan and that in turn creates protection from UVR. If you are looking to be some bronzed beach God with perfectly uniform and specific color then you are better off to going to mystic tan.  Redheads, for example, naturally produce a variant form of melanin that is yellowish-red (pheomelanin).  Do not expect a brown tan on a ginger body right away.

Know your skin type:  Knowing your skin type is just one detail which will help create a user log.  There are 10s of thousands of melanotan users worldwide who share the experience.  Raise awareness and help others who want to hear success stories, complications and failures.

Am I a good candidate for MT-II?
Melanotan is best suited for the folks with skin types I & II.  Prior sun damage, scars, tattoos, freckles, moles, hair color, etc are deciding factors prospective MT-2 users consider.  This is a question handled best through asking the audience.  Seek council other others at the Melanotan Forum.

How should I dose MT-II?
Start out small and build up.  A typical starting dose is around .25mg and max dose reaching 1mg.

Things to consider:
There is no magic pill or formula.  Few dermatologists are familiar with Melanotan.  The skin is a large, unpredictable organ.  Feel comfortable and confident with MT-II before use.  Check out as many before and after photos and user logs as you can.  A skin type I individual may have to commit months of dedication before dialing in their desired results, be patient.

How much MT-II should I buy and how long will it last?
Skin type I:  30-50mg
Skin type II:  20-30mg
Skin type III:  10mg
Should last entire summer or season

How soon will I begin to see results?
You should notice a change in your skin tone after three weeks. If you have freckles, expect them to get darker before your actual skin color changes.

How long will tan last?
A tan developed using Melanotan 2 lasts much longer than an ordinary tan.  A well-tanned person returning from a beach holiday will lose most of the tan in a month if they stop getting sun.  But if they had been using Melanotan 2 and continued on maintenance after returning, they would still have most of their tan 3 months later.

Side effects of MT-II?
Possible short-term side effects you should know about, including: nausea, appetite loss, facial flushing and increased libido. These may be noticeable during the first few days of treatment but should taper off.

Dosing an anti-histamine, such as Claritin (Loratadine), works to eliminate sides such as nausea after injecting.

Bremelanotide (PT-141)

February 13th, 2010 by peptideguide

Bremelanotide PT-141 Dosing:

Light:  .5mg
Common:  1mg
Large:  2mg

Bremelanotide (PT-141) was developed from Melanotan II, which was tested as a sunless tanning agent. PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.  Bremelanotide belongs to class of drugs called melanocortins.  In initial testing, Melanotan II did induce tanning but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects.  PT-141 is the only synthetic aphrodisiac.

In studies, bremelanotide was shown to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications, PT-141 does not act upon the vascular system, but directly increases sexual desire via the nervous system.

Window of Opportunity:
Although injected (subcutaneously), Bremelanotide has a unique window of opportunity lasting six to 72 hours! In lab trials, female rats exposed to PT-141 immediately began “flirting” with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. Women who took part in trials said that they felt a “tingling and a throbbing” along with “a strong desire to have sex.” An initial flush occurs post injection, followed by nausea which is dose dependent.  For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark. Men said PT-141 made them feel “younger and more energetic” as well as sexually interested and aroused. “You’re ready to take your pants off and go,” said user “a drug that makes you not only able to but eager to.”

Bremelanotide PT-141 Peptide:
bremelanotide peptides compared 10mg vs 2mg lyophilized product
Bremelanotide in lyophilized form comes in 10mg and 2mg vial sizes (as pictured above -notice the peptide volume).  Once reconstituted with bacteriostatic water, PT-141 can be stored in the fridge for a couple months and remain potent.  Nasal sprays, pre-mixed PT-141, pills and loose powder are not legitimate forms of Bremelanotide.  There are successful reports of snorting and nasal spray experiences…however they are few and far between.

bremelanotide chemical structure

Afamelanotide (M-I)

February 13th, 2010 by peptideguide

Melanotan One, Afamelanotide (M-I) Dosing:

Light:  .5mg
Common:  1mg
Large:  2mg

Melanotan/Afamelanotide is a synthetic version of melanocyte stimulating hormone (a-MSH).  Afamelanotide has been shown to induce skin pigmentation through melanogenisis subsequently reducing sun (UV) damage to UV exposed skin.  Studies state Melanotan as being 10 to 1000 times more potent than our natural a-MSH.
Amino acid sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 or [Nle4, D-Phe7]-a-MSH.

Melanotan One does not cause sexual arousal or aphrodisiac effects. These aspects are only found in Melanotan 2 and Bremelanotide (PT-141).

The Melanotan ???Cycle???

Allow a couple weeks before seeing UV exposure.  Sunburn is to be avoided.

Example-  Skin type II, 180lb male
Day 1-2:  .5mg each night
Day 3-6:  1mg when convenient
Day 7-10:  2mg when convenient
Day 11 on forward:  begin dosing ~6mg/week

Day 7:  10min sun bed session.  Cover face, use lotion, etc
Day 9:  10min sun bed session.  Allow face some rays and obviously continue to use lotion liberally.
Day 11:  15min sun bed session

What Skin Type Am I?
fitzpatrick skin type chart

Dosing According to Skin Type

Fitzpatrick Skin Type I:  1mg-2mg/day.  100mg total may be necessary to achieve desired color.  UV exposure after at least 20mg in system
Fitzpatrick Skin Type II:  .75mg-1.5mg/day.  60mg should be sufficient to get color.  UV exposure after 10-20mg
Fitzpatrick Skin Type III:  .5mg-1mg/day.  A sunless tan may be realistic here
Fitzpatrick Skin Type IV and beyond:  Do not use Melanotan.

Melanocytes at Work

Melanotan has a very brief half life.  The melanin precursors and activated melanocytes last for months.  Missing a dose or taking time off is just fine.

Melanotan Results

Reconstituting

Swab the stopper of both your M-I vial and the vial of the dilutent (bacteriostatic water) with an alcohol swab.

Take a syringe and draw up your bact water. The amount isn’t critical, other than making sure you know exactly how much you have used. The best rule of thumb is choose an amount that will make measuring the final product easy.

Example- 2ml(cc) per 20mg vial of M-I would mean each 10 marks on a U100 insulin syringe would equal 1mg of Melanotan (M-I)

Example- 1ml(cc) per 10mg vial of M-I would mean each 10 marks on a U100 insulin syringe would equal 1mg of Melanotan (M-I)

Avoid shooting the dilutent directly on the lyophilized powder.  The powder should almost instantly dissolve.  Gently swirl until the liquid is clear if powder did not dissolve upon contact.

Store your unused M-I in the refrigerator.  Once reconstituted, the Melanotan should be good for 4-6 weeks in the refrigerator.

Measuring

After you have successfully reconstituted your Melanotan, now you need to know how to measure the desired amount out for injection. You will want to use a U100 insulin syringe to draw out your M-I.

Since you know the amount of mg’s in your M-I vial, and you also know how much water you have diluted it with, we just divide this out as follows:
Note:  1ml = 1cc = 100 IU’s

So we take our number of mg’s of Melanotan and we divide that into the amount of dilutent we used.

Example- We used 2cc(ml) of water. We have a 20mg vial of M-I.
From our formula above we know that 1cc = 100 IU’s, so we have 200 IU’s of water.
We now divide the 200 IU’s (the amount of our water) by 20mg (the amount of our M-I)

200 IU / 20mg = 10

This 10 will perfectly correspond with the markings on a U100 insulin syringe. In our example every 10 mark on our syringe will equal 1mg of M-I.

Melanotan is injected subcutaneously.  Melanotan is still undergoing clinical trials and is not an approved drug in the US or Australia.  People use on the pretenses and understanding that it is for research purposes only.  Users who administer subcutaneously may suffer from slight nausea and flushing similar to that of Melanotan II; however, it is not reported to be as severe or last as long.

Those who develop (using the word develop loosely) moles or freckles typically do so on their first cycle.  It is rare people develop more on later cycles.  The reality is the freckles were probably present before, but were light enough that they had gone unnoticed.  If you take the drug in order to change your skin color???you can almost expect it to happen.